Examples of Research Abstracts

Scand J Work Environ Health. 2011 Nov;37(6):547-50. doi: 10.5271/sjweh.3170. Epub 2011 May 26.

Effect of brief daily exercise on headache among adults–secondary analysis of a randomized controlled trial.

Andersen LL, Mortensen OS, Zebis MK, Jensen RH, Poulsen OM.
National Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100 Copenhagen
Ø, Denmark.
This paper investigates secondary outcomes (headache) in a randomized controlled trial with physical
exercise among office workers with neck/shoulder pain.
A total of 198 office workers with frequent neck/shoulder pain were randomly allocated to either one of
two intervention groups (10 weeks of resistance training with elastic tubing for 2 or 12 minutes per
day, 5 times a week) or the control group, which received weekly health information. Secondary
outcomes included changes in frequency, intensity, and duration of headache after ten weeks.
Compared with the control group, headache frequency decreased in the 2- and 12-minute intervention
groups [0.64 days/week (95% confidence interval [95% CI]) 0.23-1.0) and 0.79 days/week (95% CI
0.37-1.2), corresponding to a 43% and 56% decrease from baseline, respectively]. Intensity and
duration of the remaining headaches were unaffected.
Two minutes of daily resistance training for ten weeks reduces headache frequency among
office workers with neck/shoulder pain. The vast number of adult workers suffering from one or
two days of weekly headaches and who could potentially comply with and benefit from brief exercise
programs stresses the applicability of our findings.

Scand J Work Environ Health. 2012 Mar;38(2):182; author reply 183.
[PubMed - indexed for MEDLINE]


Spine 2002;27(17):1835-43.

A randomized controlled trial of exercise and manipulative therapy for cervicogenic headache.
Jull G, Trott P, Potter H, Zito G, Niere K, Shirley D, et al.

This trial evaluated the effect of exercise therapy in people with cervicogenic headache (Jull 2002).
This trial found that exercise was superior to no treatment in reducing headache pain and frequency
at 1 week and 1 year after 6 weeks of treatment. Exercise was also at least as effective as manipulation.
Clin J Pain. 2011 Jun;27(5):448-56.
Subjective well-being in patients with chronic tension-type headache: effect of acupuncture, physical training, and relaxation training.
Söderberg EI, Carlsson JY, Stener-Victorin E, Dahlöf C.
Departments of Clinical Neuroscience and Rehabilitation/Physiotherapy, Institute of Neuroscience
and Physiology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Episodic tension-type headache is a common problem affecting approximately 2 of 3 of the
population. The origin of tension-type headache is multifactorial, but the pathogenesis is still unclear.
In some individuals episodic tension-type headache transforms into chronic tension-type headache
(CTTH). Subjective symptoms related to the central nervous system might affect patients subjective
well-being and quality of life.
Physical training and relaxation training seem to be preferable non-pharmacologic treatments for
improvement of central nervous system-related symptoms and subjective well-being for patients with
21317776 [PubMed - indexed for MEDLINE]

J Rehabil Med. 2010 Apr;42(4):344-9.
Effect of neck exercises on cervicogenic headache: a randomized controlled trial.
Ylinen J, Nikander R, Nykänen M, Kautiainen H, Häkkinen A.
Department of Physical Medicine and Rehabilitation, Central Hospital of Central Finland, Jyväskylä,
To compare the efficacy of three 12-month training programmes on headache and upper extremity
pain in patients with chronic neck pain.
A total of 180 female office workers, with chronic, non-specific neck pain were randomly assigned to 3
groups. The strength group performed isometric, dynamic and stretching exercises. The endurance
group performed dynamic muscle and stretching exercises. The control group performed stretching
exercises. Pain was assessed with a visual analogue scale. Each group was divided into 3 subgroups
according to headache intensity.
At the 12-month follow-up headache had decreased by 69% in the strength group, 58% in the
endurance group and 37% in the control group compared with baseline. Neck pain diminished most in
the strength group with the most severe headache (p < 0.001). In the dose analysis, one metabolic
equivalent per hour of training per week accounted for a 0.6-mm decrease in headache on the visual
analogue scale. Upper extremity pain decreased by 58% in the strength group, 70% in the endurance
group and 21% in the control group.
All of the training methods decreased headache. However, stretching, which is often recommended
for patients, was less effective alone than when combined with muscle endurance and strength
training. Care must be taken in recommending the type of training to be undertaken by patients with
severe cervicogenic headache.
20461336 [PubMed - indexed for MEDLINE]



1. Ahonen E, Hakumäki M, Mahlamäki S, Partanen J, Riekkinen P, Sivenius J. Acupuncture and
physiotherapy in the treatment of myogenic headache patients: pain relief and EMG activity.
In: Bonica JJ, Lindblom U, Iggo A editor(s). Advances in Pain Research and Therapy. Vol. 5, New
York: Raven Press, 1983:571‐6.
2. Amiri M, Jull G, Bullock‐Saxton J, Darnell R, Lander C. Cervical musculoskeletal impairment in
frequent intermittent headache. Part 2: Subjects with concurrent headache types.
Cephalalgia. 2007;27:891–898. [PubMed]
3. Ammer K, Rathkolb O. Physical therapy in occipital headaches [Physikalische Therapie bei
Hinterhauptkopfschmerzen]. Manuelle Medizin 1990;28:65‐8.
4. Antonaci F, Bono G, Chimento P. Diagnosing cervicogenic headache. J Headache Pain.
2006;7:145–148. [PubMed]
5. Antonaci F, Ghirmai S, Bono G, Sandrini G, Nappi G. Cervicogenic headache: Evaluation of the
original diagnostic criteria. Cephalalgia. 2001;21:573–583. [PubMed]
6. Bigal ME, Lipton RB. The differential diagnosis of chronic daily headaches: An algorithm‐based
approach. J Headache Pain. 2007;8 DOI 10.1007/s10194–007–0418–3.
7. Biondi DM. Physical treatments for headache: A structured review. Headache. 2005;45:738–
746. [PubMed]
8. Blau J, MacGregor E. Migraine and the neck. Headache. 1994;34:88–90. [PubMed]
9. Bogduk N. Cervicogenic headache: Anatomical basis and pathophysiological mechanisms.
Journal of Current Pain Headache Report. 2001;5:382–386.
10. Bogduk N. Headache and the neck. In: Goadsby P, Silberstein S, editors. Headache.
Melbourne, Australia: Butterworth‐Heinemann; 1997.
11. Boline PD, Kassak K, Bronfort G, Nelson C, Anderson AV. Spinal manipulation vs. amitriptyline
for the treatment of chronic tension‐type headaches: a randomized clinical trial. Journal of
Manipulative & Physiological Therapeutics 1995;18(3):148‐54.
12. Bove G, Nilsson N. Spinal manipulation in the treatment of episodic tension‐type headache: a
randomized controlled trial. JAMA 1998;280(18):1576‐9.
13. Bronfort G, Nilsson N, Haas M, et al. Non‐invasive physical treatments for chronic/recurrent
headache. Cochrane Database Syst Rev. 2004;(3) CD001878.
14. Bronfort G, Nilsson N, Haas M, Evans R, Goldsmith CH, Assendelft WJJ, Bouter LM (2004) Noninvasive
physical treatments for chronic/recurrent headache. Cochrane Database Syst Rev
15. Buzzi M, Moskowitz M. The pathophysiology of migraine: Year 2005. J Headache Pain.
2005;6:105–111. [PubMed]
16. Carlsson J, Augustinsson LE, Blomstrand C, Sullivan M. Health status in patients with tension
headache treated with acupuncture or physiotherapy. Headache 1990;30(9):593‐9.
17. Carlsson J, Fahlcrantz A, Augustinsson LE. Muscle tenderness in tension headache treated with
acupuncture or physiotherapy. Cephalalgia 1990;10(3):131‐41.
18. Carlsson J, Rosenhall U. Oculomotor disturbances in patients with tension headache treated
with acupuncture or physiotherapy. Cephalalgia 1990;10(3):123‐9.
19. Carlsson J, Wedel A, Carlsson GE, Blomstrand C. Tension headache and signs and symptoms of
craniomandibular disorders treated with acupuncture or physiotherapy. The Pain Clinic
20. Chiu TT, Lam TH, Hedley AJ. A randomized controlled trial on the efficacy of exercise for
patients with chronic neck pain. Spine. 2005; 30(1): E1–E7.
21. Diener I. The impact of cervicogenic headache on patients attending a private physiotherapy practice in Cape Town. S Afr J Physiother. 2001;57:35–39.
22. Dumas JP, Arsenault AB, Boudreau G, et al. Physical impairments in cervicogenic headache:
Traumatic vs. non‐traumatic onset. Cephalalgia. 2001;21:884–893. [PubMed]
23. Edeling J. Migraine and other chronic headaches: Preliminary report on experimental physical
treatment. S Afr J Physiother. 1974;30:2–3.
24. Edmeads J. Disorders of the neck: Cervicogenic headache. In: Silberstein SD, Lipton RB,
Dalessio DJ, editors. Wolff’s Headache and Other Head Pain. Oxford, UK: Oxford University
Press; 2001.
25. Edmondston SJ, Wallumrød ME, MacLéid F, Kvamme LS, Joebges S, Brabham GC. Reliability of
isometric muscle endurance tests in subjects with postural neck pain. Journal of Manipulative
and Physiological Therapeutics. 2008; 31(5): 348‐54
26. Falla D, Jull G, Dall’Alba P, Rainoldi A, Merletti R. An electromyographic analysis of the deep
cervical flexor muscles in performance of craniocervical flexion. Physical Therapy. 2003; 83:
27. Falla D, O’Leary S, Fagana A, Jull G. Recruitment of the deep cervical flexor muscles during a
postural‐correction exercise performed in sitting. Manual Therapy. 2007; 12: 139–143.
28. Falla D. Unravelling the complexity of muscle impairment in chronic neck pain. Man Ther.
2004;9:125–133. [PubMed]
29. Falla DL, Jull GA, Hodges PW. Patients with neck pain demonstrate reduced electromyographic
activity of the deep cervical flexor muscles during performance of the craniocervical flexion
test. Spine. 2004;29:2108–2114. [PubMed]
30. Fernandez‐de‐Las‐Penas C, Alonso‐Blanco C, Cuadrado ML, Miangolarra JC, Barriga FJ, Pareja
JA. Are manual therapies effective in reducing pain from tension‐type headache? A systematic
review. Clin J Pain. 2006;22:278–285. [PubMed]
31. Fernandez‐des‐las‐Penas C, Alonos‐Blanco C, San‐Roman J, Miangolarra‐Page J.
Methodological quality or randomized controlled trials of spinal manipulation and
mobilisation in tension‐type headache, migraine, and cervicogenic headache. J Orthop Sports
Phys Ther. 2006;36:160–169. [PubMed]
32. Fishbain DA, Cutler R, Cole B, Rosomoff HL, Rosomoff RS. International Headache Society
headache diagnostic patterns in pain facility patients. Clin J Pain. 2001;17:78–93. [PubMed]
33. Gross AR, Aker PD, Goldsmith CH, Peloso P (1996) Conservative management of mechanical
neck disorders. A systematic overview and meta‐analysis. Online J Curr Clin Trials Doc No 200–
34. Gross AR, Aker PD, Goldsmith CH, Peloso P (2000) Patient education for mechanical neck
disorders. A systematic overview and meta‐analysis. In: Cochrane Library; Issue 4, Update
Software, Oxford.
35. Haldeman S, Dagenais S. Cervicogenic headaches: A critical review. Spine J. 2001;1:31–46.
36. Hall T, Robinson K, Fujinawa O, Kiyokazu A. Inter‐tester reliability and diagnostic validity of the
cervical flexion‐rotation test in cervicogenic headache. J Manipulative & Physiol Ther. 2007
Accepted for publication.
37. Hall T, Robinson K. The flexion‐rotation test and active cervical mobility: A comparative
measurement study in cervicogenic headache. Man Ther. 2004;9:197–202. [PubMed]
38. Henry P, Dartigues J, Puymirat C, Peytour P, Lucas J. The association cervicalgia‐headaches: An
epidemiologic study. Cephalalgia. 1987;7(Suppl 6):189–190. [PubMed]
39. Hoyt WH, Shaffer F, Bard DA, Benesler JS, Blankenhorn GD, Gray JH, et al. Osteopathic
manipulation in the treatment of muscle‐contraction headache. Journal of the American
Osteopathic Association 1979;78(5):322‐5.
40. Hu H, Markson L, Lipton R, Stewart W, Berger M. Burden of migraine in the United States:
Disability and economic costs. Arch Intern Med. 1999;1:813–818. [PubMed]
41. International Headache Society The International Classification of Headache Disorders. 2nd ed.
Cephalalgia. 2004;24(Suppl 1):9–160. [PubMed]

42. Janda, V. 1988. Muscles and Cervicogenic Pain Syndromes. In Physical Therapy of the
Cervical and Thoracic Spine, ed. R. Grand. New York: Churchill Livingstone.
43. Jansen J, Sjaastad O. Cervicogenic headache: Smith/Robinson approach in bilateral cases.
Funct Neurol. 2006;21:205–210. [PubMed]
44. Jensen OK, Nielsen FF, Vosmar L. An open study comparing manual therapy with the use of
cold packs in the treatment of post‐traumatic headache. Cephalalgia 1990;10(5):241‐50.
45. Jull G, Amiri M, Bullock‐Saxton J, Darnell R, Lander C. Cervical musculoskeletal impairment in
frequent intermittent headache. Part 1: Subjects with single headaches. Cephalalgia.
2007;27:793–802. [PubMed]
46. Jull G, Barrett C, Magee R, Ho P. Further clinical clarification of the muscle dysfunction in
cervical headache. Cephalalgia 1999; 19: 179–85.
47. Jull G, Bogduk N, Marsland A. The accuracy of manual diagnosis for cervical zygapophyseal
joint pain syndromes. Med J Aust. 1988;148:233–236. [PubMed]
48. Jull G, Niere K. The cervical spine and headache. In: Boyling G, Jull G, editors. Grieve’s Modern
Manual Therapy. London, UK: Churchill Livingstone; 2004.
49. Jull G, O’leary S, Falla D. Clinical assessment of the deep cervical flexor muscles: the
craniocervical flexion test. Journal of Manipulative and Physiological Therapeutics. 2008; 31:
50. Jull G, Trott P, Potter H, Zito G, Niere K, Shirley D, Emberson J, Marschner I, Richardson C. A
RCT of exercise and manipulative therapy for cervicogenic headache. Spine. 2002; 27: 1835‐
51. Jull G, Zito G, Trott P, Potter H, Shirley D, Richardson C. Inter‐examiner reliability to detect
painful upper cervical joint dysfunction. Aust J Physiother. 1997;43:125–129. [PubMed]
52. Jull GA, Falla DL, Vicenzino B, Hodges PW. The effect of therapeutic exercise on activation of
the deep cervical flexor muscles in people with chronic neck pain. Manual Therapy. 2009; 14:
53. Jull GA, O’Leary SP, Falla DL. Clinical Assessment of the Deep Cervical Flexor Muscles: The
Craniocervical Flexion Test. Journal of Manipulative and Physiological Therapeutics. 2008; 525‐
54. Jull GA, Stanton WR. Predictors of responsiveness to physiotherapy management of
cervicogenic headache. Cephalalgia. 2005;25:101–108. [PubMed]
55. Kay TM, Gross A, Santaguida PL, Hoving J, Goldsmith C, Bronfort G (2005) Cervical Overview
Group. Exercises for mechanical neck disorders. Cochrane Database Syst Rev 3:CD004250.
56. Keller E, Bzdek VM. Effects of therapeutic touch on tension headache pain. Nursing Research
57. Kirchmann M. Migraine with aura: New understanding from clinical epidemiologic studies.
Curr Opin Neurol. 2006;19:286–293. [PubMed]
58. Landtblom AM, Fridriksson S, Boivie J, Hillman J, Johansson G, Johansson I. Sudden onset
headache: A prospective study of features, incidence and causes. Cephalalgia. 2002;22:354–
360. [PubMed]
59. Lipton RB, Stewart WF. The epidemiology of migraine. Eur Neurol. 1994;34(Suppl 2):6–11.
60. Maitland G, Hengeveld E, Banks K, English K. Maitland’s Vertebral Manipulation. 6th ed.
London, UK: Butterworth Heinemann; 2001.
61. Marcus DA, Scharff L, Mercer S, Turk DC. Nonpharmacological treatment for migraine:
incremental utility of physical therapy with relaxation and thermal biofeedback. Cephalalgia
62. McDonnell M, Sahrmann S, Van Dillen L. A specific exercise program and modification of
postural alignment for the treatment of cervicogenic headache: A case report. J Orthop Sports
Phys Ther. 2005;35:3–15. [PubMed]
63. Mongini F, Ciccone G, Rota E, Ferrero L, Ugolini A, Evangelista A, Ceccarelli M, Galassi C.
Effectiveness of an educational and physical programme in reducing headache, neck and shoulder pain: a workplace controlled trial. Cephalalgia. 2008;28:541–552. doi:

10.1111/j.1468‐2982.2008.01551.x. [PubMed] [Cross Ref]

64. Mongini F, Ciccone G, Rota E, Ferrero L, Ugolini A, Evangelista A, Ceccarelli M, Galassi C. Long
term benefits of an educational and physical program on headache, and neck and shoulder
pain in a working community. J Pain. 2009;10:1138–1145. doi: 10.1016/j.jpain.2009.01.324.
65. Nicholson GG, Gaston J. Cervical headache. J Orthop Sports Phys Ther. 2001;31:184–193.
66. Nilsson N, Christensen HW, Hartvigsen J. The effect of spinal manipulation in the treatment of
cervicogenic headache. Journal of Manipulative & Physiological Therapeutics 1997;20(5):326‐
67. Nilsson N. A randomized controlled trial of the effect of spinal manipulation in the treatment
of cervicogenic headache. Journal of Manipulative & Physiological Therapeutics
68. Nilsson N. The prevalence of cervicogenic headache in a random population sample of 20–59‐
year‐olds. Spine. 1995;20:1884–1888. [PubMed]
69. O’Leary S, Jull G, Kim M, Vincenzino B. Specificity in Retraining Craniocervical Flexor Muscle
Performance. Journal of Orthopaedic and Sports Physical Therapy. 2007; 37(1):3‐9.
70. Ogince M, Hall T, Robinson K. The diagnostic validity of the cervical flexion‐rotation test in
C1/2‐related cervicogenic headache. Man Ther. 2007;12:256–262. [PubMed]
71. Parker GB, Pryor DS, Tupling H. Why does migraine improve during a clinical trial? Further
results from a trial of cervical manipulation for migraine. Australian & New Zealand Journal of
Medicine 1980;10(2):192‐8.
72. Parker GB, Tupling H, Pryor DS. A controlled trial of cervical manipulation of migraine.
Australian & New Zealand Journal of Medicine 1978;8(6):589‐93.
73. Pfaffenrath V, Kaube H. Diagnostics of cervicogenic headache. Funct Neurol. 1990;5:159–164.
74. Reich BA. Non‐invasive treatment of vascular and muscle contraction headache: a
comparative longitudinal clinical study. Headache 1989;29(1):34‐41.
75. Reid S, Rivett D, Callister R, Katekar M. Sustained natural apophyseal glides (SNAGS) are an
effective treatment for cervicogenic dizziness. Man Ther. 2007
76. Roth JK, Roth RS, Weintraub JR, Simons DG. Cervicogenic headache caused by myofascial
trigger points in the sternocleidomastoid: A case report. Cephalalgia. 2007;27:375–380.
77. Sandmark H, Nisell R. Validity of five common manual neck pain provocation tests. Scand J
Rehabil Med. 1995;27:131–136. [PubMed]
78. Sjaastad O, Bakketeig LS. Migraine without aura: Comparison with cervicogenic headache.
Vaga study of headache epidemiology. Acta Neurol Scand. 2007;PMID:18031560.
79. Sjaastad O, Bakketeig LS. Prevalence of cervicogenic headache: Vaga study of headache
epidemiology. Acta Neurol Scand. 2008;117:170–183.
80. Sjaastad O, Bovim G. Cervicogenic headache: The differentiation from common migraine. An
overview. Funct Neurol. 1991;6:93–100. [PubMed]
81. Sjaastad O, Fredriksen T, Pareja J, Stolt‐Nielsen A, Vincent M. Co‐existence of cervicogenic
headache and migraine without aura. Funct Neurol. 1999;14:209–218. [PubMed]
82. Sjaastad O, Fredriksen TA, Pfaffenrath V. Cervicogenic headache: Diagnostic criteria.
Headache. 1990;30:725–726. [PubMed]
83. Sjogren T, Nissinen KJ, Jarvenpaa SK, Ojanen MT, Vanharanta H, Malkia EA. Effects of a
workplace physical exercise intervention on the intensity of headache and neck and shoulder
symptoms and upper extremity muscular strength of office workers: a cluster randomized
controlled cross‐over trial. Pain. 2005;116:119–128. doi: 10.1016/j.pain.2005.03.031.

84. Solomon S, Elkind A, Freitag F, Gallagher RM, Moore K, Swerdlow B, et al. Safety and
effectiveness of cranial electrotherapy in the treatment of tension headache. Headache
85. Stewart WF, Lipton RB, Kolodner K, Liberman J, Sawyer J. Reliability of the migraine disability
assessment score in population‐based sample of headache sufferers. Cephalalgia.
1999;19:107–114. doi: 10.1046/j.1468‐2982.1999.019002107.x. [PubMed]
86. Stochkendahl M, Christensen H, Hartvigsen J, et al. Manual examination of the spine: A
systematic review of reproducibility. J Manipulative & Physiol Ther. 2006;29:475–485.
87. Stovner L, Hagen K, Jensen R, et al. The global burden of headache: A documentation of
headache prevalence and disability worldwide. Cephalalgia. 2007;27:193–210. [PubMed]
88. Stovner LJ, Hagen K, Jensen R, Katsarava Z, Lipton RB, Scher AI, Steiner TJ, Zwart J‐A. The
global burden of headache: a documentation of headache prevalence and disability
worldwide. Cephalalgia. 2007;27:193–210. doi: 10.1111/j.1468‐2982.2007.01288.x. [PubMed]
89. van Suijlekom HA, Lame I, Stomp‐van den Berg SG, Kessels AG, Weber WE. Quality of life of
patients with cervicogenic headache: A comparison with control subjects and patients with
migraine or tension‐type headache. Headache. 2003;43:1034–1041. [PubMed]
90. Vincent M. Validation of criteria for cervicogenic headache. Funct Neurol. 1998;13:74–75.
91. Vincent MB, Luna RA. Cervicogenic headache: A comparison with migraine and tension‐type
headache. Cephalalgia. 1999;19(Suppl 25):11–16. [PubMed]
92. von Piekartz HJ, Schouten S, Aufdemkampe G. Neurodynamic responses in children with
migraine or cervicogenic headache versus a control group: A comparative study. Man Ther.
2007;12:153–160. [PubMed]
93. Watson DH, Trott PH. Cervical headache: An investigation of natural head posture and upper
cervical flexor muscle performance. Cephalalgia. 1993;13:272–284. discussion 232. [PubMed]
94. Wiendels NJ, Knuistingh Neven A, Rosendaal FR, Spinhoven P, Zitman FG, Assendelft WJ,
Ferrari MD. Chronic frequent headache in the general population: prevalence and associated
factors. Cephalalgia. 2006;26:1434–1442. doi: 10.1111/j.1468‐2982.2006.01210.x. [PubMed]
95. Zito G, Jull G, Story I. Clinical tests of musculoskeletal dysfunction in the diagnosis of
cervicogenic headache. Man Ther. 2006;11:118–129. [PubMed]
96. Zwart JA. Neck mobility in different headache disorders. Headache. 1997;37:6–11. [PubMed]